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CAS RN: 288315-09-3 | 產品號碼: M2742
Methylcobalamin Hydrate
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| 產品號碼 | M2742 |
| 純度/分析方法 | >98.0%(N) |
| 分子式 / 分子量 | C__6__3H__9__1CoN__1__3O__1__4P·xH__2O = 1,344.40 (as Anhydrous) |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Refrigerated (0-10°C) |
| 應避免的情況 | Light Sensitive,Heat Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 288315-09-3 |
| 相關CAS RN | 13422-55-4 |
| Reaxys-RN | 18144941 |
| PubChem Substance ID | 253661235 |
| MDL編號 | MFCD00082483 |
產品規格
| Appearance | Red to Dark red to Brown powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 %(calcd.on anh.substance) |
| Water | max. 12.0 % |
性質
| 水溶性 | Slightly soluble |
GHS
相關法規
| RTECS # | GG3745000 |
運輸資料
| HS編碼* | 2936.26-000 |
Application
ビタミンB12の生理学的等価体，メチルコバラミン
Methylcobalamin, a water soluble vitamin B12 analog, is equivalent physiologically to vitamin B12. Methylcobalamin functions as a coenzyme in a number of reactions, including the oxidation of fatty acids and the synthesis of DNA. It also works in conjugation with folic acid [F0043] (Vitamin B9) in the synthesis of the amino acid L-methionine [M0099] and it required for normal production of red blood cells. Although methylcobalamin is necessary for nervous system maintenance, the mechanisms are not entirely known. Methylcobalamin can be used to prevent or treat pathology arising from a lack of vitamin B12. (The product is for research purpose only.)
References
- How a protein binds B12: a 3.0 Å x-ray structure of B12-binding domains of methionine synthase
- Similarities and Differences between Cobalamins and Cobaloximes. Accurate Structural Determination of Methylcobalamin and of LiCl- and KCl-Containing Cyanocobalamins by Synchrotron Radiation
- Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency (a review)
- Cobalamin-dependent methyltransferases (a review)
- Vitamin B12-derivatives - enzyme cofactors and ligands of proteins and nucleic acids (a review)
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