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CAS RN: 22373-78-0 | 產品號碼: M2573
Monensin Sodium Salt
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纯度/分析方法: >98.0%(T)
別名
- Monensin A Sodium Salt
- Sodium Monensin
- Sodium (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-2-Ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-[2,2'-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoate
文件：
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| 產品號碼 | M2573 |
| 純度/分析方法 | >98.0%(T) |
| 分子式 / 分子量 | C__3__6H__6__1NaO__1__1 = 692.86 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 22373-78-0 |
| PubChem Substance ID | 468592207 |
| MDL編號 | MFCD00077826 |
產品規格
| Appearance | White to Almost white powder to crystaline |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +55.0 to +60.0 deg(C=1.0, MeOH) |
| NMR | confirm to structure |
性質
| 熔點 | 264 °C(dec.) |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H300 : Fatal if swallowed. H371 : May cause damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | JH2830000 |
運輸資料
| UN編號 | UN2811 |
| 類別 | 6.1 |
| 包裝類別 | II |
| HS編碼* | 2941.90-000 |
Application
Exosome research
References
- Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions
- Exosome Release Is Regulated by a Calcium-dependent Mechanism in K562 Cells
Application
Monensin Sodium Salt: A Monovalent Ion-Selective Ionophore Antibiotic
Monensin sodium salt is a monovalent ion-selective ionophore antibiotic, and facilitates the transmembrane exchange of principally sodium ions for protons, and therefore it shows a variety of biological properties including Golgi. Through its ability to affect pH and the sodium-potassium balance of a cell, monensin can induce cell death in Gram-positive bacteria. (The product is for research purpose only.)
References
- Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity (a review)
- Forty years of monensin for the control of coccidiosis in poultry (a review)
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