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CAS RN: 38304-91-5 | 產品號碼: M1389
| 產品號碼 | M1389 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__9H__1__5N__5O = 209.25 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 38304-91-5 |
| Reaxys-RN | 886240 |
| PubChem Substance ID | 87573342 |
| Merck Index(14) | 6203 |
| MDL編號 | MFCD00063409 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Solubility in Acetic acid | almost transparency |
性質
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | UV8200000 |
運輸資料
| HS編碼* | 2933.59-000 |
Application
Minoxidil: An Opener of Vascular Smooth Muscle ATP Dependent K+ Channels
Minoxidil is an antihypertensive vasodilator agent and hair growth promoter that is metabolized by sulfation to the active compound, minoxidil sulfate [CAS: 83701-22-8]. The mode of action of the effects are still not completely understood, but the most plausible explanation is that minoxidil sulfate acts as an opener of vascular smooth muscle ATP dependent K+ (KATP) channels. Additionally, transdermal minoxidil delivery systems have been developed to increase the skin permeability.
References
- Enzymic and nonenzymic sulfation mechanisms in the biological actions of minoxidil (a review)
- Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells
- Minoxidil sulfate is the active metabolite that stimulates hair follicles (a review)
- Transdermal delivery of minoxidil with block copolymer nanoparticles
- Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery
- Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil
考研文獻
TCIMail
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