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CAS RN: 82034-46-6 | 產品號碼: L0327
Loteprednol Etabonate
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纯度/分析方法: >98.0%(HPLC)
別名
- HGP 1
- P 5604
- CDDD 5604
- Chloromethyl (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate
- (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylic Acid Chloromethyl Ester
文件：
| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 50MG |
NT$2,080
|
15 | 聯繫我們 |
| 250MG |
NT$8,160
|
10 | 17 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準，敬請留意。
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +38.0 to +42.0 deg(C=1, dioxane) |
性質
| 熔點 | 225 °C(dec.) |
| 比旋光 [α]D | 40° (C=1,Dioxane) |
| Maximum Wavelength | 244 nm |
| 水溶性 | Insoluble |
| Degree of solubility in water | 0.0005 grm/l 25 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H361 : Suspected of damaging fertility or the unborn child. H413 : May cause long lasting harmful effects to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相關法規
運輸資料
| HS編碼* | 2937.22-000 |
Application
Loteprednol Etabonate: A “Soft” Corticosteroid
Loteprednol etabonate is a classed as a “soft” corticosteroid designed based on the “inactive metabolite approach”. It is locally metabolized by hydrolysis to the corresponding inactive cortienic acid derivative, and thus limiting or eliminating the associated systemic and local side effects. Corticosteroids play a role in cellular signaling, immune function, inflammation and protein regulation, and they are commonly used to control inflammation. However, there is no generally accepted explanation for the mechanism of action of corticosteroids. Loteprednol etabonate is used to treat inflammations of the eye in clinical. (The product is for research purpose only.)
References
- Soft drugs--10. Blanching activity and receptor binding affinity of a new type of glucocorticoid: loteprednol etabonate
- Metabolism, distribution, and transdermal permeation of a soft corticosteroid, loteprednol etabonate
- Ocular absorption and distribution of loteprednol etabonate, a soft steroid, in rabbit eyes
- Soft steroids: a new approach to the treatment of inflammatory airways diseases (a review)
TCIMail
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