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CAS RN: 6150-58-9 | 產品號碼: L0319
Lycorine Hydrochloride Monohydrate
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| 產品號碼 | L0319 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__6H__1__7NO__4·HCl·H__2O = 341.79 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器 | 100MG-Glass Bottle with Plastic Insert （閲覽圖片）, 25MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 6150-58-9 |
| 相關CAS RN | 2188-68-3 |
| Reaxys-RN | 6105700 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +41.0 to +45.0 deg(C=2.9, water) |
| Water | max. 7.0 % |
性質
| 熔點 | 215 °C(dec.) |
| 比旋光 [α]D | 43° (C=2.9,H2O) |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H301 : Toxic if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
| RTECS # | OL2910000 |
運輸資料
| UN編號 | UN2811 |
| 類別 | 6.1 |
| 包裝類別 | III |
| HS編碼* | 2934.99-000 |
Application
Lycorine Hydrochloride: The Major Bioactive Alkaloid Found in Amaryllidaceae Family Plant
Lycorine hydrochloride is the major bioactive alkaloid found in Amaryllidaceae family plant, a represent traditional Chinese medicinal herb. Lycorine and its derivatives have been shown to have various biological activities, including anti-leukemia, anti-tumor, anti-angiogenesis, anti-virus, anti-bacteria, anti-inflammation, and anti-malaria. They also exert many biological functions, such as inhibition of acetylcholinesterase. (The product is for research purpose only.)
References
- Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure-Activity Relationship and Mechanistic Insight
- Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives (a review)
- Lycorine and its derivatives for anticancer drug design (a review)
- Multiple biological functions and pharmacological effects of lycorine (a review)
- LCMS and GCMS for the screening of alkaloids in natural and in vitro extracts of Leucojum aestivum
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