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CAS RN: 132866-11-6 | 產品號碼: L0282
Lercanidipine Hydrochloride
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產品號碼 | L0282 |
純度/分析方法 | >98.0%(T)(HPLC) |
分子式 / 分子量 | C__3__6H__4__1N__3O__6·HCl = 648.20 |
外觀與形狀(20°C) | Solid |
儲存條件 | Refrigerated (0-10°C) |
應避免的情況 | Light Sensitive,Heat Sensitive |
包裝和容器 | 1G-Glass Bottle with Plastic Insert (閲覽圖片), 200MG-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 132866-11-6 |
相關CAS RN | 100427-26-7 |
Reaxys-RN | 7406263 |
PubChem Substance ID | 253660808 |
Merck Index(14) | 5446 |
MDL編號 | MFCD07773089 |
產品規格
Appearance | Light orange to Yellow to Green powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
性質
熔點 | 195 °C(dec.) |
溶解性(可溶於) | Methanol |
GHS
圖形表示 |
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信號詞 | Warning |
危險性說明 | H302 : Harmful if swallowed. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
運輸資料
HS編碼* | 2933.39-000 |
Application
Paraptosis research
Reference
- Lercanidipine Synergistically Enhances Bortezomib Cytotoxicity in Cancer Cells via Enhanced Endoplasmic Reticulum Stress and Mitochondrial Ca2+ Overload
- Pharmacological in vitro studies of the new 1,4-dihydropyridine calcium antagonist lercanidipine
- L. Guarneri, P. Angelico, M. Ibba, E. Poggesi, C, Taddei, A. Leonardi, R. Testa, Arzneim.-Forsch. 1996, 46, 15.
- Lercanidipine (Rec 15/2375): a novel 1,4-dihydropyridine calcium antagonist for hypertension (a review)
- Development and evaluation of buccoadhesive controlled release tablets of lercanidipine
- Oral self emulsifying powder of lercanidipine hydrochloride: Formulation and evaluation
- Determination of lercanidipine hydrochloride and its impurities in tablets
Application
Lercanidipine Hydrochloride: A Vascular-Selective Dihydropyridine Calcium Channel Antagonist
Lercanidipine hydrochloride is a long-lasting and vascular-selective dihydropyridine calcium channel antagonist that causes vasodilatation by blocking the influx of calcium ions through L-type calcium channels in cell membranes. Recently, formulations of lercanidipine hydrochloride have been studied to improve its bioavailability. (The product is for research purpose only.)
References
考研文獻
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