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CAS RN: 7724-76-7 | 產品號碼: I1221
6-(γ,γ-Dimethylallylamino)purine Riboside
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| 產品號碼 | I1221 |
| 純度/分析方法 | >97.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__5H__2__1N__5O__4 = 335.36 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| 包裝和容器 | 500MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 7724-76-7 |
| Reaxys-RN | 629507 |
| MDL編號 | MFCD00005741 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 144.0 to 148.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 146 °C |
GHS
相關法規
| RTECS # | AU7404910 |
運輸資料
| HS編碼* | 2934.99-000 |
Application
N6-Isopentenyladenosine (i6A): A Bioactive Base-Modified Ribonucleoside at a Specific Position of tRNA
N6-Isopentenyladenosine (i6A) is one of the longest known base-modified ribonucleoside and occurs only at a specific position in tRNA found in bacteria and eukaryotes. It has pronounced cytokinin activity in several plant tissues, high anticancer activity in a wide range of cell lines, and exhibits pronounced antiviral activity including SARS-CoV-2.1-4) In addition, the role of N6-isopentenyladenosine in a subset of tRNAs in gene expression has been associated with translational fidelity, translation speed, skewed gene expression, and non-sense suppression.4,5) (The product is for research purpose only.)
References
- 1) N6-Isopentenyladenosine: a potential therapeutic agent for a variety of epithelial cancers
- 2) Forodesine and Riboprine Exhibit Strong Anti-SARS-CoV‑2 Repurposing Potential: In Silico and In Vitro Studies
- 3) Regioselective 1-N-Alkylation and Rearrangement of Adenosine Derivatives
- 4) Biological and pharmacological roles of N6-isopentenyladenosine: an emerging anticancer drug (a review)
- 5) The modified base isopentenyladenosine and its derivatives in tRNA (a review)
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