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CAS RN: 113-52-0 | 產品號碼: I0971
Imipramine Hydrochloride
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| 產品號碼 | I0971 |
| 純度/分析方法 | >98.0%(HPLC) |
| 分子式 / 分子量 | C__1__9H__2__4N__2·HCl = 316.87 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 應避免的情況 | Light Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 113-52-0 |
| 相關CAS RN | 50-49-7 |
| Reaxys-RN | 3576963 |
| PubChem Substance ID | 253661339 |
| Merck Index(14) | 4920 |
| MDL編號 | MFCD00012669 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 171.0 to 175.0 °C |
性質
| 熔點 | 173 °C |
| Maximum Wavelength | 260 nm |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | HO1925000 |
運輸資料
| HS編碼* | 2933.99-000 |
Application
Imipramine hydrochloride: An Inhibitor of Serotonin or Noradrenaline Re-Uptake Transporters
Imipramine hydrochloride is the first tricyclic antidepressant agent synthesized in 1948. Imipramine works as an inhibitor of serotonin (5-hydroxytryptamine, 5HT [S0370]) or L-noradrenaline [A0906] re-uptake transporters in brain neurons, but it also inhibits the release of acetylcholine from nerves. (The product is for research purpose only.)
References
- Inhibition of the uptake of tritiated catechol amines by antidepressant and related agents
- "Behavioral despair" in rats and mice: strain differences and the effects of imipramine
- Imipramine hydrochloride (a review)
- Transdermal drug delivery of imipramine hydrochloride. I. Effect of terpenes
- Depression and antidepressants: Insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters (a review)
考研文獻
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