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CAS RN: 482-27-9 | 產品號碼: I0861
Isopimpinellin
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| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 10MG |
NT$9,400
|
10 | 聯繫我們 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
當地經銷商
洽詢。
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| 產品號碼 | I0861 |
| 純度/分析方法 | >98.0%(GC) |
| 分子式 / 分子量 | C__1__3H__1__0O__5 = 246.22 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 包裝和容器 | 10MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 482-27-9 |
| Reaxys-RN | 262337 |
| PubChem Substance ID | 172089036 |
| MDL編號 | MFCD00017407 |
產品規格
| Appearance | Light yellow to Yellow to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 148.0 to 152.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 150 °C |
| Maximum Wavelength | 268(MeOH) nm |
GHS
相關法規
| RTECS # | LV1049200 |
運輸資料
| HS編碼* | 2932.99-000 |
Application
A Bioactive Component in Apiaceae (Umbelliferae)
Isopimpinellin, a kind of furanocoumarin, is found in Apiaceae (Umbelliferae) such as celery and parsley, and Citrus such as lime and grapefruit.1) It has been known that furanocoumarins as typified by bergamottin induce photodermatosis, which is produced in plants as a defense against herbivorous animals.2) However, isopimpinellin does not have phototoxicity,3) but has an antifungal effect, an insecticidal effect and an antifeeding effect.4) In addition, Cnidii Monnieri Fructus, dried fruits of Cnidium monnieri CUSSON (Apiaceae), contains isopimpinellin, and is used as a crude drug in traditional Chinese medicine. The evidence of an antipruritic effect has been revealed.5) It has been also reported that isopimpinellin regulates cytochromes P450 (hepatic detoxicating enzymes) and inhibits tumorigenesis induced by the metabolites of polycyclic aromatic hydrocarbons (PAHs).6) (The product is for research purpose only.)
References
- 1) The natural coumarins: occurrence, chemistry and biochemistry
- 2) Furanocoumarin induction in wild parsnip: Evidence for an induced defense against herbivores
- 3) a) Furocoumarins of Heracleum Laciniatum: isolation, phototoxicity, absorption and action spectra studies
- b) Isopimpinellin is not phototoxic in a chick skin assay
- 4) a) Antifungal activity of coumarins
- b) Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila
melanogaster - c) Osthol and isopimpinellin from Fructus cnidii for the control of Dactylogyrus intermedius in Carassius
auratus - d) Phloroglucinol-type furocoumarins, a group of potent naturally-occurring insect antifeedants
- 5) a) Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice
- b) Antipruritic effect of Cnidii Monnieri Fructus (fruits of Cnidium monnieri Cusson)
- 6) a) Inhibition and inactivation of murine hepatic ethoxy- and pentoxyresorufin O-dealkylase by naturally
occurring coumarins - b) Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor
initiation by 7,12-dimethylbenz[α]anthracene in SENCAR mice - c) Effects of naturally occurring coumarins on hepatic drug metabolizing enzymes in mice
考研文獻
產品文件 （部分產品的分析圖譜無法提供，敬請諒解。）