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CAS RN: 14047-28-0 | 產品號碼: H1291
(R)-9-(2-Hydroxypropyl)adenine
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| 產品號碼 | H1291 |
| 純度/分析方法 | >98.0%(T)(HPLC) |
| 分子式 / 分子量 | C__8H__1__1N__5O = 193.21 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Moisture Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 14047-28-0 |
| PubChem Substance ID | 253662428 |
| MDL編號 | MFCD07369451 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 198.0 to 202.0 °C |
| Specific rotation [a]20/D | -41.0 to -46.0 deg(C=1,EtOH) |
| NMR | confirm to structure |
性質
| 熔點 | 200 °C |
| 比旋光 [α]D | -42° (C=1,EtOH) |
| 溶解性（可溶於） | Dimethylformamide |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
運輸資料
| HS編碼* | 2933.99-000 |
Application
An Intermediate for the Synthesis of Tenofovir, a Nucleotide Reverse Transcriptase Inhibitor
This compound is an intermediate for the synthesis of tenofovir [T3006], a nucleotide reverse transcriptase (RT) inhibitor and antiretroviral agent.
References
- Synthesis of enantiomeric N-(2-phosphonomethoxypropyl) derivatives of purine and pyrimidine bases. I. The stepwiseapproach
- Practical synthesis of the anti-HIV drug, PMPA
- Process Improvements for the Manufacture of Tenofovir Disoproxil Fumarate at Commercial Scale
- The synthesis of tenofovir and its analogues via asymmetric transfer hydrogenation
考研文獻
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