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CAS RN: 198637-52-4 | 產品號碼: G0503
Gadobutrol Monohydrate
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| 產品號碼 | G0503 |
| 純度/分析方法 | >98.0%(T) |
| 分子式 / 分子量 | C__1__8H__3__1GdN__4O__9·H__2O = 622.74 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Hygroscopic,Heat Sensitive |
| 包裝和容器 | 100MG-Glass Bottle with Plastic Insert （閲覽圖片）, 25MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 198637-52-4 |
| Reaxys-RN | 15557943 |
| PubChem Substance ID | 468591918 |
| MDL編號 | MFCD29917846 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(Chelometric Titration) | min. 98.0 % |
| Water | 2.6 to 3.1 % |
性質
| 溶解性（不溶於） | Ethanol |
GHS
相關法規
運輸資料
| HS編碼* | 2846.90-000 |
Application
Gadobutrol: A Paramagnetic Macrocyclic Contrast Agent for MRI
Gadobutrol, gadolinium complex, is a paramagnetic macrocyclic contrast agent used for magnetic resonance imaging (MRI). Contrast-enhanced MRI has become a mainstay of imaging with unlimited applications. In a magnetic field, gadobutrol shortens the T1 (spin-lattice or longitudinal) relaxation times, which improves MR image quality. Gadobutrol is often used as an aqueous solution (1 mmol/mL) mixed with calcobutrol sodium, tris(hydroxymethyl)aminomethane (another name: trometamol) and hydrochloric acid (for pH adjustment). (The product is for research purpose only.)
References
- Longitudinal assessment of blood-brain barrier leakage during epileptogenesis in rats. A quantitative MRI study
- Signal Increase on Unenhanced T1-Weighted Images in the Rat Brain after Repeated, Extended Doses of Gadolinium-Based Contrast Agents: Comparison of Linear and Macrocyclic Agents
- Gadobutrol: A Review of Its Use for Contrast-Enhanced Magnetic Resonance Imaging in Adults and Children (a review)
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