5-Fluorouracil

References

• 5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice
  • F. Sedlmayer, A.-K. Woischnig, V. Unterreiner, F. Fuchs, D. Baeschlin, N. Khanna, M. Fussenegger, Nucleic Acids Res. 2021, 49, e73.
• The Role of Drug Repurposing in the Development of Novel Antimicrobial Drugs: Non-Antibiotic Pharmacological Agents as Quorum Sensing-Inhibitors
  • M. Gajdács, G. Spengler, Antibiotics 2019, 8, 270
• 5-Fluorouracil reduces biofilm formation in Escherichia coli K-12 through global regulator AriR as an antivirulence compound
  • C. Attila, A. Ueda, T.K. Wood, Appl. Microbiol. Biotechnol. 2009, 82, 525.
• Uracil influences quorum sensing and biofilm formation in Pseudomonas aeruginosa and fluorouracil is an antagonist
  • A. Ueda, C. Attila, M. Whiteley, T.K. Wood, Microb. Biotechnol. 2009, 2, 62.

References

• Fluorouracil: biochemistry and pharmacology (a review)
  • H. M. Pinedo, G. F. Peters, J. Clin. Oncol. 1988, 6, 1653.
• 5-Fluorouracil: mechanisms of action and clinical strategies (a review)
  • D. B. Longley, D. P. Harkin, P. G. Johnston, Nat. Rev. Cancer 2003, 3, 330.
• Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism (a review)
  • G. J. Peters, H. H. J. Backus, S. Freemantle, B. van Triest, G. Codacci-Pisanelli, C. L. van der Wilt, K. Smid, J. Lunec, A. H. Calvert, S. Marsh, H. L. McLeod, E. Bloemena, S. Meijer, G. Jansen, C. J. van Groeningen, H. M. Pinedo, Biochim. Biophys. Acta, Mol. Basis Dis. 2002, 1587, 194.
• The prodrugs of 5-fluorouracil (a review)
  • M. Malet-Martino, P. Jolimaitre, R. Martino, Curr. Med. Chem. Anti-Canc. Agents 2002, 2, 267.
• Determination of 5-fluorouracil in environmental samples by solid-phase extraction and high-performance liquid chromatography with ultraviolet detection
  • G. Micoli, R. Turci, M. Arpellini, C. Minoia, J. Chromatogr. B 2001, 750, 25.
• A review of analytical methods for the determination of 5-fluorouracil in biological matrices
  • M. Breda, S. Barattè, Anal. Bioanal.Chem. 2010, 397, 1191.

References

• 16-16 dimethyl prostaglandin E₂ reduces 5-fluorouracil-induced and mitomycin C-induced gastric mucosal injury in the dog
  • P. Bright-Asare, G. L. Kauffman Jr., Cancer 1984, 54, 28.
• Effects of acid antisecretory drugs on mucus barrier of the rat against 5-fluorouracil-induced gastrointestinal mucositis
  • Y. Saegusa, T. Ichikawa, T. Iwai, Y. Goso, T. Ikezawa, M. Nakano, N. Shikama, K. Saigenji, K. Ishihara, Scand. J. Gastroenterol. 2008, 43, 531.

Reference

• The anti-cancer drug-induced pica in rats is related to their clinical emetogenic potential
  • K. Yamamoto, M. Nakai, K. Nohara, A. Yamatodani, Eur. J. Pharmacol. 2007, 554, 34.