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CAS RN: 19130-96-2 | 產品號碼: D5612
1-Deoxynojirimycin
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| 產品號碼 | D5612 |
純度/分析方法 
|
>98.0%(HPLC) |
| 分子式 / 分子量 | C__6H__1__3NO__4 = 163.17 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive |
| 包裝和容器
|
250MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 19130-96-2 |
| Reaxys-RN | 1524395 |
| PubChem Substance ID | 468591452 |
| Merck Index(14) | 2905 |
| MDL編號 | MFCD00063474 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Melting point | 201.0 to 205.0 °C |
| Specific rotation | +44.0 to +48.0 deg(C=1, water) |
| NMR | confirm to structure |
性質
| 熔點 | 203 °C |
GHS
相關法規
| RTECS # | TN4350300 |
運輸資料
| HS編碼* | 2933.39-000 |
Application
1-Deoxynojirimycin: An α-Glucosidase Inhibitor
1-Deoxynojirimycin, an alkaloid azasugar, is a bioactive compound that exists in mulberry leaves and Commelina communis (dayflower) as well as from several bacterial strains. It has been reported that 1-deoxynojirimycin has diverse pharmacological properties as an α-glucosidase inhibitor, such as antihyperglycemic, anti-obesity, and antiviral activities.1,2) Furthermore, 1-deoxynojirimycin and its N-alkylated derivative (miglitol [M2302]: N-butyldeoxynojirimycin) have been used as α-glucosidase inhibitors that smooth post-prandial peak plasma glucose levels and thus improve glycemic control.3) (The product is for research purpose only.)
References
- 1) 1-deoxynojirimycin: occurrence, extraction, chemistry, oral pharmacokinetics, biological activities and in silico target fishing (a review)
- 2) Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions
- 3) N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis
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