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CAS RN: 987-78-0 | 產品號碼: C3438
Cytidine 5'-Diphosphocholine
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產品號碼 | C3438 |
純度/分析方法 | >98.0%(HPLC) |
分子式 / 分子量 | C__1__4H__2__6N__4O__1__1P__2 = 488.33 |
外觀與形狀(20°C) | Solid |
儲存條件 | Refrigerated (0-10°C) |
儲存在惰性氣體下 | Store under inert gas |
應避免的情況 | Air Sensitive,Hygroscopic,Heat Sensitive |
CAS RN | 987-78-0 |
Reaxys-RN | 4170138 |
PubChem Substance ID | 468591111 |
Merck Index(14) | 2319 |
MDL編號 | MFCD00868097 |
產品規格
Appearance | White to Almost white powder to crystaline |
Purity(HPLC) | min. 98.0 area% |
Melting point | 209.0 to 213.0 °C |
Specific rotation [a]20/D | +17.0 to +21.0 deg(C=1, H2O) |
Solubility in Water | almost transparency |
NMR | confirm to structure |
性質
熔點 | 211 °C |
水溶性 | Soluble |
GHS
相關法規
RTECS # | GA4027000 |
運輸資料
HS編碼* | 2934.99-000 |
Application
Citicoline: An Essential Intermediate in the Major Pathway for the Biosynthesis of the Structural Phospholipids
Citicoline (CDP-choline), a naturally occurring endogenous nucleoside, is an essential intermediate in the major pathway for the biosynthesis of the structural phospholipids of cell membranes, including neurons. It has been reported that citicoline activates the biosynthesis of structural phospholipids in the neuronal membrane, increases cerebral metabolism and increases the level of various neurotransmitters, including acetylcholine and dopamine. Therefore, citicoline is used for the treatment of CNS disorders, in clinical. (The product is for research purpose only.)
References
- Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline (a review)
- Citicoline: neuroprotective mechanisms in cerebral ischemia (a review)
- Cytidine 5'-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
- Neuroprotective Properties of Citicoline: Facts, Doubts and Unresolved Issues (a review)
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