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CAS RN: 31251-41-9 | 產品號碼: C3181
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
![Thumbnail of 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one](/medias/C3181.jpg?context=bWFzdGVyfHJvb3R8MTQ2MzJ8aW1hZ2UvanBlZ3xhRFU0TDJnNVl5ODRPVE0wTWpNek1EYzVPRE00TDBNek1UZ3hMbXB3Wnd8ZjI4MTk0ZWIzMzY4YjhiNmY4OTM5NjRiNGVlYzU1ZmFhNzdkOTA5MGUwNWFjZjUxZjM0MDZkMWRkMzY1Zjc2Yg "8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one")
![Chemical Structure of 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one](/medias/C3181.jpg?context=bWFzdGVyfHJvb3R8NDY4Nzh8aW1hZ2UvanBlZ3xhREJqTDJoaVl5ODRPVEl3T0RFMk9EYzNOVGs0TDBNek1UZ3hMbXB3Wnd8ZWIwODRjMzM1NTcwOTliYWMwYjJmMjY1MzYyMDMyNDYyMTI1NDgxZDI3YzBlZTg5Mzc3YTAxZjQzZGIxZWZmYQ "8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one")
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![8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one")
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產品規格
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 103.0 to 107.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 105 °C |
| 溶解性（可溶於） | Methanol |
GHS
相關法規
運輸資料
| HS編碼* | 2933.99-000 |
Application
A Related Substance of Loratadine and Desloratadine
The reagent is a related substance of loratadine [L0223] and desloratadine [D3787] which are histamine receptor antagonists.
References
- Hydroxylated metabolites of loratadine: an example of conformational diastereomers due to atropisomerism
- LC determination of loratadine and related impurities
- Capillary electrophoresis determination of loratadine and related impurities
- Rapid separation of desloratadine and related compounds in solid pharmaceutical formulation using gradient ion-pair chromatography
PubMed Literature
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