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CAS RN: 3650-09-7 | 產品號碼: C2488
Carnosic Acid (Synthetic)
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| 產品號碼 | C2488 |
| 純度/分析方法 | >97.0%(T)(HPLC) |
| 分子式 / 分子量 | C__2__0H__2__8O__4 = 332.44 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Frozen (<0°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Light Sensitive,Air Sensitive,Heat Sensitive |
| 包裝和容器 | 100MG-Glass Bottle with Plastic Insert （閲覽圖片）, 20MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 3650-09-7 |
| Reaxys-RN | 2707918 |
| PubChem Substance ID | 125307807 |
| MDL編號 | MFCD02259459 |
產品規格
| Appearance | White to Yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| Specific rotation [a]20/D | +182 to +195 deg(C=1, MeOH) |
性質
| 熔點 | 190 °C |
| 比旋光 [α]D | 184° (C=1,MeOH) |
GHS
相關法規
運輸資料
| HS編碼* | 2918.99-000 |
Application
Efflux pump research / Efflux pump inhibitor
Carnosic acid is a compound known as an abietane diterpene. According to the study using Staphylococcus aureus, carnosic acid (10 μg/ml) showed a 2-fold potentiation of tetracycline activity against XU212 (TetK possessing strain) and 8-fold potentiation of erythromycin activity against RN4220 (Msr possessing strain).1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Antibacterial and resistance modifying activity of Rosmarinus officinalis
- Rosmarinus officinalis as an Antioxidant
- Antioxidant Activity of a Rosemary Extract and Its Constituents, Carnosic Acid, Carnosol, and Rosmarinic Acid, in Bulk Oil and Oil-in-Water Emulsion
- Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
- Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism
- Carnosic acid and carnosol potently inhibit human 5-lipoxygenase and suppress pro-inflammatory responses of stimulated human polymorphonuclear leukocytes
- Carnosic acid, a new class of lipid absorption inhibitor from sage
- 1)M. Tada, T. Ohkanda, J. Kurabe, Chem. Pharm. Bull. 2010, 58, 27.
- 2)M. Tada, PCT Int. Appl. WO 2009060547, 2009.
- 3)M. Tada, TCIMAIL 2012, number 150, 2.
Application
Notice
This product is the synthetic carnosic acid. For your reference, recent reviews on carnosic acid after 2015 are shown on anther carnosic acid [C3477] product application on the website. (The product is for research purpose only.)
Application
Antioxidant study
References
Application
Neuron protective effects study
Reference
Application
Inhibition of adipocyte differentiation study
Reference
Application
Inhibition of human 5-Lipoxigenase study
Reference
Application
Inhibition of lipid absorption study
Reference
Application
Synthesis of carnosic acid
Reference
考研文獻
文章/手冊
TCIMail
[TCIMAIL No.153] Antioxidant Carnosic Acid by Chemical Synthesis[Product Highlights] Antioxidant Carnosic Acid by Chemical Synthesis
產品文件 （部分產品的分析圖譜無法提供，敬請諒解。）
