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CAS RN: 24729-96-2 | 產品號碼: C2257
Clindamycin Phosphate
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產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(Nonaqueous Titration) | min. 97.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +115.0 to +130.0 deg(C=1, H2O)(calcd.on anh.substance) |
| Water | max. 6.0 % |
性質
| 熔點 | 114 °C |
| 比旋光 [α]D | 122° (C=1,H2O) |
| 水溶性 | Soluble |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | GF2625000 |
運輸資料
| HS編碼* | 2941.90-000 |
Application
Clindamycin Phosphate: A Water Soluble Clindamycin
Clindamycin phosphate is a prodrug of lincosamide antibiotic clindamycin hydrochloride [C2256], and is designed as a highly water soluble form of the poorly water soluble parent compound clindamycin. Meanwhile, clindamycin phosphate has been used as a chiral selector.
References
- Parenteral development of clindamycin-2-phosphate (a review)
- K. W. Riebe, T. O. Oesterling, Bull. Parenteral Drug Assoc. 1972, 26, 139.
- Case Study: Clindamycin 2-Phosphate, A Prodrug of Clindamycin (a review)
- Investigation of enantiomeric separation of basic drugs by capillary electrophoresis using clindamycin phosphate as a novel chiral selector
- Evaluation of the enantioseparation capability of the novel chiral selector clindamycin phosphate towards basic drugs by micellar electrokinetic chromatography
考研文獻
文章/手冊
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