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CAS RN: 56-75-7 | 產品號碼: C2255
Chloramphenicol
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| 包裝 | 價格 | 同一天 | 2-3个工作日 |
|---|---|---|---|
| 25G |
NT$1,920
|
16 | ≥100 |
| 250G |
NT$9,960
|
11 | ≥60 |
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
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產品規格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Argentometric Titration) | min. 98.0 % |
| Melting point | 149.0 to 153.0 °C |
| Specific rotation [a]20/D | +17.0 to +21.0 deg(C=5, EtOH) |
性質
| 熔點 | 151 °C |
| 比旋光 [α]D | 20° (C=5,EtOH) |
| 溶解性（可溶於） | Ether, Chloroform |
| 溶解性（不溶於） | Benzene |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H361 : Suspected of damaging fertility or the unborn child. H372 : Causes damage to organs through prolonged or repeated exposure. H373 : May cause damage to organs through prolonged or repeated exposure. H340 : May cause genetic defects. H350 : May cause cancer. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相關法規
| RTECS # | AB6825000 |
運輸資料
| HS編碼* | 2941.40-000 |
Application
RNA aptamer research
Reference
- RNA aptamers to the peptidyl transferase inhibitor chloramphenicol
Application
Chloramphenicol: A Broad Spectrum Antibiotic and a Selective Reagent Genetically Engineered Cells
Chloramphenicol was originally isolated from the soil bacterium Streptomyces venezuelae in 1947. Chloramphenicol and a congener thiamphenicol [T2802] can now be made by chemical synthesis. Chloramphenicol has a highly stable which can be stored for prolonged times at room temperature. It has a broad spectrum of antibiotic activity including Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, while it is not effective against Pseudomonas aeruginosa. Chloramphenicol inhibits protein synthesis in susceptible organisms by binding to specific nucleotides in 23S rRNA within the 50S subunit of a bacterial ribosome. However, chloramphenicol causes side effects including bone marrow suppression and aplastic anemia. Chloramphenicol is used in molecular biology as a selective reagent most commonly to isolate bacteria coupled to a gene coding for chloramphenicol resistance, which is one of the most frequently used selection markers for obtaining transgenic cells.
References
- Chloramphenicol: Relation of Structure to Activity and Toxicity (a review)
- Structural basis for the interaction of antibiotics with the peptidyl transferase center in eubacteria
- Molecular basis of bacterial resistance to chloramphenicol and florfenicol (a review)
- High-copy-number and low-copy-number plasmid vectors for lacZ α-complementation and chloramphenicol- or kanamycin-resistance selection
- A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives
- Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae
考研文獻
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