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CAS RN: 485-71-2 | 產品號碼: C0347
| 產品號碼 | C0347 |
| 純度/分析方法 | >98.0%(T) |
| 分子式 / 分子量 | C__1__9H__2__2N__2O = 294.40 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 應避免的情況 | Light Sensitive |
| CAS RN | 485-71-2 |
| Reaxys-RN | 5286475 |
| PubChem Substance ID | 87565480 |
| SDBS (AIST Spectral DB) | 15236 |
| Merck Index(14) | 2286 |
| MDL編號 | MFCD00006783 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 90.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -105 to -110 deg(C=1, EtOH) |
性質
| 熔點 | 206 °C |
| 比旋光 [α]D | -108° (C=1,EtOH) |
| 水溶性 | Insoluble |
| 溶解性（可溶於） | Ether, Alcohol, Chloroform |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H302 : Harmful if swallowed. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相關法規
| RTECS # | GD2975000 |
運輸資料
| HS編碼* | 2939.20-000 |
Application
Cinchonidine: A Cinchona Alkaloid with both Biological and Asymmetric Catalytic Activity
Cinchona alkaloids (quinine [Q0028], quinidine [Q0006], cinchonidine and cinchonine [C0350]) is isolated from Cinchona plants, and have been used as traditional medicines for the treatment of malaria as well as several diseases.1) Recently studies has revealed that cinchona alkaloids exerts antimalarial, anti-obesity, anti-cancer, anti-oxidant, anti-inflammatory, anti-microbial activity.2) On the other hand, in organic chemistry, cinchona alkaloids have been used as useful catalysts in asymmetric synthesis.3,4) (The product is for research purpose only.)
References
- 1) Quantitative determination of major alkaloids in Cinchona bark by supercritical fluid chromatography
- 2) Spectrum of biological properties of cinchona alkaloids: a brief review
- 3) Asymmetric Mannich Reactions of β-Keto Esters with Acyl Imines Catalyzed by Cinchona Alkaloids
- 4) In situ characterization of the adsorption of cinchona chiral modifiers on platinum surfaces (a review)
考研文獻
TCIMail
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