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CAS RN: 67-97-0 | 產品號碼: C0314
Cholecalciferol
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| 產品號碼 | C0314 |
| 純度/分析方法 | >98.0%(HPLC) |
| 分子式 / 分子量 | C__2__7H__4__4O = 384.65 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Frozen (<0°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| 包裝和容器 | 1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 67-97-0 |
| PubChem Substance ID | 125308742 |
| SDBS (AIST Spectral DB) | 10003 |
| Merck Index(14) | 10019 |
| MDL編號 | MFCD00078131 |
產品規格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +103 to +112 deg(C=0.5, EtOH) |
| Absorbance | 0.450 to 0.510(10mg/L, EtOH, 263.0 to 267.0 nm) |
| NMR | confirm to structure |
性質
| 熔點 | 86 °C |
| 比旋光 [α]D | 108° (C=0.5,EtOH) |
| 水溶性 | Insoluble |
| 溶解性（可溶於） | Alcohol, Chloroform |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled. H360 : May damage fertility or the unborn child. H372 : Causes damage to organs through prolonged or repeated exposure. H413 : May cause long lasting harmful effects to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P262 : Do not get in eyes, on skin, or on clothing. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相關法規
| RTECS # | VS2900000 |
運輸資料
| UN編號 | UN2811 |
| 類別 | 6.1 |
| 包裝類別 | II |
| HS編碼* | 2936.29-000 |
Application
Efflux pump inhibitor
References
- Action of cholecalciferol and alpha-tocopherol on Staphylococcus aureus efflux pumps
Application
Cholecalciferol (Vitamin D3): A Compound for the Maintenance of Normal Skeleton Architecture and Mineral Homeostasis
Cholecalciferol (Vitamin D3) is known for the maintenance of normal skeleton architecture and mineral homeostasis. Vitamin D3 is synthesized from 7-dehydrocholesterol [CAS: 434-16-2] in the skin under the influence of UV light, or it is obtained from food, especially fatty fish. The transformation (hydroxylation) of vitamin D3 is catalyzed by enzymes in the liver and the kidney to produce calcitriol [C3078] (other name: 1α,25-dihydroxyvitamin D3), the active form of vitamin D3. Calcitriol is active in the regulation of the absorption of calcium from the gastrointestinal tract. (The product is for research purpose only.)
References
- Overview of general physiologic features and functions of vitamin D (a review)
- Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease (a review)
- Enzymes involved in the activation and inactivation of vitamin D (a review)
- Vitamin D physiology (a review)
- Analytical measurement and clinical relevance of vitamin D3 C3-epimer (a review)
- The role of vitamin D in reducing cancer risk and progression (a review)
考研文獻
文章/手冊
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