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CAS RN: 1715-30-6 | 產品號碼: A3389
Alexidine Dihydrochloride
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| 產品號碼 | A3389 |
| 純度/分析方法 | >98.0%(HPLC)(N) |
| 分子式 / 分子量 | C__2__6H__5__6N__1__0·2HCl = 581.72 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件 | Frozen (-20°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Hygroscopic,Heat Sensitive |
| 包裝和容器 | 100MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 1715-30-6 |
| Reaxys-RN | 5698790 |
| PubChem Substance ID | 468590270 |
| MDL編號 | MFCD00082369 |
產品規格
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 223.0 to 227.0 °C |
性質
| 熔點 | 225 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防範說明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相關法規
運輸資料
| HS編碼* | 2925.29-000 |
Application
Alexidine Dihydrochloride: A Cationic Bis(Biguanide) Antimicrobial Agent
Alexidine dihydrochloride is a cationic bis(biguanide) antimicrobial agent. It has been reported that alexidine binds to lipopolysaccharide and lipoteichoic acid and prevents microbial cell activation.1,2) In addition, alexidine induces apoptosis in cancer cell line, and inhibits the protein tyrosine phosphatase mitochondrion-1 (PTPM1).3,4) (The product is for research purpose only.)
References
- 1) Alexidine and chlorhexidine bind to lipopolysaccharide and lipoteichoic acid and prevent cell activation by antibiotics
- 2) Alexidine dihydrochloride has broad-spectrum Activities against diverse fungal pathogens
- 3) Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent
- 4) Pharmacological Targeting of the Mitochondrial Phosphatase PTPMT1
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