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Zwitterionic monomers contain both cationic and anionic groups in the same molecule, and are able to add superhydrophilic and/or antifouling features to the materials. As a result they are often applied to surface modification of water treatment filters or medical equipment including stents and catherters, nanomicelles for drug delivery system (DDS), and surface modification for biosensors to reduce measurement noise, etc. TCI contributes to these researches and industries by offering various zwitterionic monomers. Our product line-up includes a phosphobetaine monomer which has a biomembrane-mimetic phosphorylcholine group, sulfobetaine and carboxybetaine monomers, whose polymerizable functional groups are acrylate and methacrylate esters, acrylamides or methacrylamides. In addition to monofunctional monomers, TCI also has a bifunctional monomer suitable as cross-linker in our catalog.
Products
Phosphobetaine Monomer (containing phosphorylcholine structure) Carboxybetaine Monomers
- M3185
- 2-[[2-(Methacryloyloxy)ethyl]dimethylammonio]acetate
- M2359
- 3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propionate
- A3279
- 3-[(3-Acrylamidopropyl)dimethylammonio]propanoate
- M1971
- 3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propane-1-sulfonate
- M3295
- 4-[[2-(Methacryloyloxy)ethyl]dimethylammonio]butane-1-sulfonate
- A3367
- 3-[[2-(Acryloyloxy)ethyl]dimethylammonio]propane-1-sulfonate
- B6130
- 3-[Bis[2-(methacryloyloxy)ethyl](methyl)ammonio]propane-1-sulfonate
- U0119
- 3-[(3-Methacrylamidopropyl)dimethylammonio]propane-1-sulfonate
- M3296
- 4-[(3-Methacrylamidopropyl)dimethylammonio]butane-1-sulfonate
- A3361
- 3-[(3-Acrylamidopropyl)dimethylammonio]propane-1-sulfonate
Applications
- Low protein absorption
- M2005:
Protein adsorption from human plasma is reduced on phospholipid polymers - M1971, M2359:
Superlow Fouling Sulfobetaine and Carboxybetaine Polymers on Glass Slides - A3279:
Ultralow Fouling and Functionalizable Surface Chemistry Based on a Zwitterionic Polymer Enabling Sensitive and Specific Protein Detection in Undiluted Blood Plasma
- M2005:
- Surface modification
- M2005:
Protein resistant surfaces: Comparison of acrylate graft polymers bearing oligo-ethylene oxide and phosphorylcholine side chains - M2359:
Polydopamine-Based Simple and Versatile Surface Modification of Polymeric Nano Drug Carriers - A3279:
Novel Zwitterionic-Polymer-Coated Silica Nanoparticles - M2005, M1971, M3185:
Biodegradable zwitterionic polymer membrane coating endowing nanoparticles with ultra-long circulation and enhanced tumor photothermal therapy
- M2005:
- Biocompatible micelle
- M2005:
Synthesis of Well-Defined Amphiphilic Block Copolymers Having Phospholipid Polymer Sequences as a Novel Biocompatible Polymer Micelle Reagent - M2359:
Highly hemocompatible zwitterionic micelles stabilized by reversible cross-linkage for anti-cancer drug delivery - M3185:
Micelles with ultralow critical micelle concentration as carriers for drug delivery
- M2005:
- Cell adhesion material
- M2005:
Protein adsorption and cell adhesion on cationic, neutral, and anionic 2-methacryloyloxyethyl phosphorylcholine copolymer surfaces - M2359:
Carboxybetaine Methacrylate-Modified Nylon Surface for Circulating Tumor Cell Capture
- M2005:
- Hydrogel
- M2005:
Soft contact lens biomaterials from bioinspired phospholipid polymers - M2359:
Zwitterionic hydrogels implanted in mice resist the foreign-body reaction - A3279:
Novel Zwitterionic-Polymer-Coated Silica Nanoparticles - M1971, M2359:
Injectable, self-healable zwitterionic cryogels with sustained microRNA - cerium oxide nanoparticle release promote accelerated wound healing - A3361:
Zwitterionic nanocomposite hydrogels as effective wound dressings
- M2005:
- Protein purification
- M2359:
Transforming protein-polymer conjugate purification by tuning protein solubility
- M2359:
- Biological substance sensors
- M2005, M3185, U0119, M1971:
Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer
- M2005, M3185, U0119, M1971: