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CAS RN: 74711-43-6 | Product Number: Z0021

Zaltoprofen


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-(10,11-Dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic Acid
Product Documents:
1G
NT$2,000
7   2   It can be shipped in about 2 weeks after ordering
5G
NT$6,840
7   1   It can be shipped in about 3-4 weeks after ordering

* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact our distributor in Taiwan to order our product.
* The storage conditions are subject to change without notice.


Product Number Z0021
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__1__4O__3S = 298.36 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Condition to Avoid Light Sensitive
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 74711-43-6
Reaxys Registry Number 6770548
PubChem Substance ID 160871191
Merck Index (14) 10112
MDL Number

MFCD00864323

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 135.0 to 139.0 °C
Properties (reference)
Melting Point 137 °C
Solubility in water Insoluble
Solubility (soluble in) Methanol
Solubility (slightly sol. in) Benzene, Ethanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# HQ2526700
Transport Information:
H.S.code* 2934.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Studies on Nonsteroidal Anti-Inflammatory Drugs (NSAID)
References

Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells

S. Kawai, S. Nishida, M. Kato, Y. Furumaya, R. Okamoto, T. Koshino, Y. Mizushima, Eur. J. Pharmacol. 1998, 347, 87.

Zaltoprofen inhibits bradykinin-induced responses by blocking the activation of second messenger signaling cascades in rat dorsal root ganglion cells

H. Tang, A. Inoue, K. Oshita, K. Hirate, Y. Nakata, Neuropharmacology 2005, 48, 1035.

Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid. 1st Communication: Inhibitory effects on rat paw edema

K. Tsurumi, K. Kyuki, M. Niwa, S. Kokuba, H. Fujimura, Arzneim.-Forsch. 1986, 36, 1796.

Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid in rat and mouse

T. Kameyama, T. Nabeshima, S. Yamada, M. Sato, Arzneim.-Forsch. 1987, 37, 19.


PubMed Literature


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Life Science
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