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CAS RN: 1098-60-8 | Product Number: T3389
Triflupromazine Hydrochloride
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 10-[3-(Dimethylamino)-1-propyl]-2-(trifluoromethyl)phenothiazine Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
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|---|---|---|---|---|---|
| 5G |
NT$2,058
|
1 | 0 | It can be shipped in about 2 weeks after ordering |
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| Product Number | T3389 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__8H__1__9F__3N__2S·HCl = 388.88 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 1098-60-8 |
| Related CAS RN | 146-54-3 |
| Reaxys Registry Number | 3801519 |
| PubChem Substance ID | 354333718 |
| Merck Index (14) | 9685 |
| MDL Number | MFCD00058103 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 174.0 to 179.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 177 °C |
| Maximum Absorption Wavelength | 305 nm (H__2O) |
| Solubility in water | Soluble |
| Solubility (soluble in) | Acetone, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | SO8925000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2934.30-000 |
Application
Triflupromazine Hydrochloride: A Classical Phenothiazine Typical Antipsychotic Agent
Triflupromazine hydrochloride is a classical phenothiazine typical antipsychotic agent such as trifluoperazine dihydrochloride[T2849]and perphenazine[P1970]. The mode of action of the phenothiazines currently not clear, but the antipsychotic and antianxiety effects are believed to be basically evoked by the limbic system and its connections with the hypothalamus. For reference, 2-(trifluoromethyl)phenothiazine[T1407]is a mother nucleus of triflupromazine. (The product is for research purpose only.)
References
- 10-(3-Dimethylaminopropyl)-2-(trifluoromethyl)phenothiazine hydrochloride (VESPRIN) and related compounds. I
- Phenothiazine drugs. Structure-activity relations explained by a conformation that mimics dopamine
- Inhibition of calmodulin by phenothiazines and related drugs: structure-activity relationships
- Spectroscopic studies on the binding of bioactive phenothiazine compounds to human serum albumin
- Extractive spectrophotometric determination of some phenothiazine derivatives in pharmaceutical preparations
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