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CAS RN: 119302-91-9 | Product Number: R0099
Rocuronium Bromide
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Purity: >90.0%(T)
Synonyms:
Product Documents:
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Product Number | R0099 |
Purity / Analysis Method | >90.0%(T) |
Molecular Formula / Molecular Weight | C__3__2H__5__3BrN__2O__4 = 609.69 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 119302-91-9 |
Related CAS RN | 143558-00-3 |
Reaxys Registry Number | 7161858 |
PubChem Substance ID | 253659588 |
Merck Index (14) | 8246 |
MDL Number | MFCD00867768 |
Specifications
Appearance | White to Light yellow to Light orange powder to crystal |
Purity(HPLC)(CAD) | min. 90.0 area% |
Purity(Nonaqueous Titration) | min. 90.0 % |
Specific rotation [a]20/D | +28.5 to +32.0 deg(C=1, 0.05mol/L HCl)(calcd.on anh.substance) |
Water | max. 6.0 % |
Properties (reference)
Melting Point | 169 °C |
Specific Rotation | 30° (C=1,0.05mol/L HCl) |
GHS
Signal Word | Warning |
Hazard Statements | H320 : Causes eye irritation. |
Precautionary Statements | P264 : Wash skin thoroughly after handling. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
Related Laws:
Transport Information:
H.S.code* | 2934.99-000 |
Application
Rocuronium Bromide: A Nicotinic Acetylcholine Receptor Antagonist
Rocuronium bromide is a muscle relaxant in the category of non-depolarizing blocking agents. Rocuronium bromide has antagonistic properties that target the neuromuscular nicotinic acetylcholine receptor, and has a shorter time of onset of action than vecuronium bromide [V0120]. (The product is for research purpose only.)
References
- Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969
- Rocuronium: The newest aminosteroid neuromuscular blocking drug
- Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors
- Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey
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