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CAS RN: 1041434-82-5 | Product Number: P2892
Peramivir Trihydrate
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Purity: >97.0%(T)(HPLC)
Synonyms:
- BCX-1812 Trihydrate
- (1S,2S,3R,4R)-3-[(S)-1-Acetamido-2-ethylbutyl]-4-guanidino-2-hydroxycyclopentane-1-carboxylic Acid Trihydrate
- (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic Acid Trihydrate
Product Documents:
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Product Number | P2892 |
Purity / Analysis Method | >97.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__5H__2__8N__4O__4·3H__2O = 382.46 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive,Heat Sensitive |
CAS RN | 1041434-82-5 |
Reaxys Registry Number | 18582192 |
PubChem Substance ID | 468592766 |
MDL Number | MFCD22417093 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 97.0 area% |
Purity(Volumetric Analysis) | min. 97.0 % |
Specific rotation | -124 to -132 deg (C=1, water) |
NMR | confirm to structure |
Properties (reference)
Solubility in water | Slightly soluble |
Solubility (insoluble in) | Dimethylformamide |
GHS
Related Laws:
Transport Information:
H.S.code* | 2925.29-000 |
Application
Peramivir: An Inhibitor of Influenza Virus Neuraminidase
Peramivir (BCX-1812, RWJ-270201) is an inhibitor of influenza virus neuraminidase, which is an enzyme that releases viral particles from the plasma membrane of infected cells. (The product is for research purpose only.)
References
- Bcx-1812 (rwj-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design
- Comparison of efficacies of RWJ-270201, zanamivir, and oseltamivir against H5N1, H9N2, and other avian influenza viruses
- Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance (a review)
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