Maximum quantity allowed is 999
Please select the quantity
CAS RN: 894-71-3 | Product Number: N0957
Nortriptyline Hydrochloride
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine Hydrochloride
- 10,11-Dihydro-5-(N-methyl-3-aminopropylidene)-5H-dibenzo[a,d]cycloheptene Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
NT$2,940
|
12 | 26 | It can be shipped in about 2 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | N0957 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__1N·HCl = 299.84 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 894-71-3 |
| Related CAS RN | 72-69-5 |
| Reaxys Registry Number | 4163872 |
| PubChem Substance ID | 253662334 |
| Merck Index (14) | 6715 |
| MDL Number | MFCD00058024 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 216.0 to 220.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 218 °C |
| Maximum Absorption Wavelength | 237 nm (H__2O) |
| Solubility in water | Slightly soluble |
| Solubility (soluble in) | Ethanol |
| Solubility (insoluble in) | Ether, Benzene, Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | HP0175000 |
Transport Information:
| H.S.code* | 2921.49-000 |
Application
三環性抗うつ薬ノルトリプチリン
Nortriptyline hydrochloride is a tricyclic antidepressant. The mechanism of action is currently not clear, but it is assumed that nortriptyline inhibits the reuptake of noradrenaline [A0906] in brain. Nortriptyline is metabolized by P450 enzyme CYP2D6 into trans-10-hydroxynortriptyline which is reported as an active form. Recently, nortriptyline hydrochloride is mainly used for smoking cessation. (The product is for research purpose only.)
References
- Nortriptyline hydrochloride (a review of the physical properties of it)
- 10-hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes
- The Metabolic Fate of Amitriptyline, Nortriptyline and Amitriptylinoxide in Man (a review)
- Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: A multi-level, single-sample approach
- Nortriptyline for smoking cessation: A review
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.