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CAS RN: 159857-80-4 | Product Number: M3224
MC-Val-Cit-PAB-OH
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Purity: >98.0%(HPLC)(N)
Synonyms:
- N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
- 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[(S)-1-[[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-5-ureidopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]hexanamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
NT$7,640
|
11 | 0 | Contact Us | |
| 500MG |
NT$26,760
|
5 | 21 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | M3224 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__8H__4__0N__6O__7 = 572.66 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 159857-80-4 |
| Reaxys Registry Number | 15438807 |
| PubChem Substance ID | 468592347 |
| MDL Number | MFCD26142966 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 2925.19-000 |
Application
A Peptide Linker Designed for Antibody-Drug Conjugate (ADC)
This product is a peptide linker designed for Antibody-Drug Conjugate (ADC) which concept is to use an antibody to deliver a cytotoxic drug (payload) selectively to a target such as a tumor-associated antigen.
References
- Cathepsin B-Labile Dipeptide Linkers for Lysosomal Release of Doxorubicin from Internalizing Immunoconjugates: Model Studies of Enzymatic Drug Release and Antigen-Specific In Vitro Anticancer Activity
- Antibody-Drug Conjugates for Cancer Therapy
- Design, Synthesis, and Biological Evaluation of Antibody-Drug Conjugates Comprised of Potent Camptothecin Analogues
Articles/Brochures
TCIMAIL
[Featured Products] Enzymatically Cleavable Linkers for Antibody-Drug Conjugates (ADCs)[TCIMAIL No.183] Dipeptides Degradable by Enzyme in Lysosome
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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