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CAS RN: 147591-46-6 | Product Number: I1108
ID 8
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Purity: >98.0%(GC)
Synonyms:
- 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Product Documents:
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Product Number | I1108 |
Purity / Analysis Method | >98.0%(GC) |
Molecular Formula / Molecular Weight | C__1__6H__1__4N__2O__4 = 298.30 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (-20°C) |
Condition to Avoid | Light Sensitive,Heat Sensitive |
Packaging and Container | 10MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 147591-46-6 |
Reaxys Registry Number | 5825601 |
PubChem Substance ID | 468592099 |
MDL Number | MFCD00593367 |
Specifications
Appearance | Light yellow to Amber to Dark green powder to crystal |
Purity(GC) | min. 98.0 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | 266 °C(dec.) |
GHS
Related Laws:
Transport Information:
H.S.code* | 2933.99-000 |
Application
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) Inhibitor
ID 8 (1) was reported as an indole derivative that can sustain embryonic stem cell self-renewal in long-term culture.1)1 inhibits dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2) 1 supports Wnt-induced human embryonic stem cell proliferation and survival without fibroblast growth factor (FGF) and tumor growth factor-β (TGF-β) supplementation.2)
References
- 1) Indole derivatives sustain embryonic stem cell self-renewal in long-term culture
- 2) Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion
Articles/Brochures
TCIMAIL
[TCIMAIL No.188] Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) InhibitorProduct Documents (Note: Some products will not have analytical charts available.)
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