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CAS RN: 113-52-0 | Product Number: I0971
Imipramine Hydrochloride
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Purity: >98.0%(HPLC)
Synonyms:
- 10,11-Dihydro-N,N-dimethyl-5H-dibenzo[b,f]azepine-5-propanamine Hydrochloride
- 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepine Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
NT$1,880
|
18 | ≥80 | It can be shipped in about 2 weeks after ordering | |
| 5G |
NT$4,080
|
24 | 2 | It can be shipped in about 2 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | I0971 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__4N__2·HCl = 316.87 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 113-52-0 |
| Related CAS RN | 50-49-7 |
| Reaxys Registry Number | 3576963 |
| PubChem Substance ID | 253661339 |
| Merck Index (14) | 4920 |
| MDL Number | MFCD00012669 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 171.0 to 175.0 °C |
Properties (reference)
| Melting Point | 173 °C |
| Maximum Absorption Wavelength | 260 nm |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | HO1925000 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Imipramine hydrochloride: An Inhibitor of Serotonin or Noradrenaline Re-Uptake Transporters
Imipramine hydrochloride is the first tricyclic antidepressant agent synthesized in 1948. Imipramine works as an inhibitor of serotonin (5-hydroxytryptamine, 5HT [S0370]) or L-noradrenaline [A0906] re-uptake transporters in brain neurons, but it also inhibits the release of acetylcholine from nerves. (The product is for research purpose only.)
References
- Inhibition of the uptake of tritiated catechol amines by antidepressant and related agents
- "Behavioral despair" in rats and mice: strain differences and the effects of imipramine
- Imipramine hydrochloride (a review)
- Transdermal drug delivery of imipramine hydrochloride. I. Effect of terpenes
- Depression and antidepressants: Insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters (a review)
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