Maximum quantity allowed is 999
Please select the quantity
CAS RN: 88321-09-9 | Product Number: E1337
E-64d [for Biochemical Research]
×
![]()
×
![E-64d [for Biochemical Research]](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "E-64d [for Biochemical Research]")
Purity: >95.0%(HPLC)
Synonyms:
- Loxistatin
- Ethyl (2S,3S)-3-[[(2S)-4-Methyl-1-[(3-methylbutyl)amino]-1-oxo-2-pentanyl]carbamoyl]-2-oxiranecarboxylate
- (2S,3S)-3-[[(2S)-4-Methyl-1-[(3-methylbutyl)amino]-1-oxo-2-pentanyl]carbamoyl]-2-oxiranecarboxylic Acid Ethyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 5MG |
NT$4,160
|
10 | 1 |
| 25MG |
NT$14,200
|
5 | 8 |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | E1337 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__3__0N__2O__5 = 342.44 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 88321-09-9 |
| Reaxys Registry Number | 5354546 |
| PubChem Substance ID | 468591716 |
| MDL Number | MFCD00132883 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation [a]20/D | +48.0 to +53.0 deg(C=1, EtOH) |
Properties (reference)
| Melting Point | 126 °C |
| Specific Rotation | 49° (C=1,MeOH) |
GHS
Related Laws:
| RTECS# | RR0404300 |
Transport Information:
| H.S.code* | 2924.29-000 |
Application
E-64d: A Potent and Irreversible Cysteine Protease Inhibitor
Cysteine proteases are enzymes containing nucleophilic cysteine thiol that are important in protein degradation pathway. E-64d (loxistatin) is a cell-permeable ethyl ester of E-64c which is a potent and irreversible cysteine protease inhibitor.
References
- In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64
- Thiol protease-specific inhibitor E-64 arrests human epidermoid carcinoma A431 cells at mitotic metaphase
- Determination of a cysteine protease inhibitor and its ethyl ester in mouse serum and muscle by liquid chromatography-mass spectrometry
- プロテアーゼインヒビターとプロドラッグデザイン
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.