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CAS RN: 209216-23-9 | Product Number: E0899
Entecavir Monohydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydrate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 50MG |
NT$6,000
|
4 | Contact Us |
| 200MG |
NT$18,080
|
22 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | E0899 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__1__5N__5O__3·H__2O = 295.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 209216-23-9 |
| Related CAS RN | 142217-69-4 |
| Reaxys Registry Number | 14632881 |
| PubChem Substance ID | 253660820 |
| Merck Index (14) | 3595 |
| MDL Number | MFCD09754448 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +34.0 to +38.0 deg(C=0.25, H2O)(calcd.on anh.substance) |
| Water | 4.0 to 9.0 % |
Properties (reference)
| Melting Point | 259 °C(dec.) |
| Specific Rotation | 36° (C=0.25,H2O) |
| Degree of solubility in water | 2.4 g/l |
| Solubility (soluble in) | Dimethylformamide |
| Solubility (slightly sol. in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Cefdinir: A Third-Generation Cephalosporin More Active Against Gram-Positive Organisms
Entecavir (ETV or BMS-200475), a deoxyguanosine analog, is rapidly phosphorylated in vivo to the active intracellular 5'-triphosphate form that inhibits replication of hepatitis B virus (HBV) and shows reduced activity against other viruses, including HIV-1, influenza and herpes simplex viruses. Entecavir is a nucleoside reverse transcriptase inhibitor (NRTI). It inhibits reverse transcription in the viral replication process. (The product is for research purpose only.)
References
- BMS-200475, a novel carbocyclic 2'-deoxyguanosine analog with potent and selective anti-hepatitis B virus activity in vitro
- Metabolic studies on BMS-200475, a new antiviral compound active against hepatitis B virus
- Efficacies of entecavir against lamivudine-resistant hepatitis B virus replication and recombinant polymerases in vitro
- Potent efficacy of entecavir (BMS-200475) in a Duck model of hepatitis B virus replication
- Inhibition of hepatitis B virus polymerase by entecavir
- Entecavir: A review of its use in chronic hepatitis B
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