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CAS RN: 101968-85-8 | Product Number: B5324
N-tert-Butylcarbamoyl-L-tert-leucine

Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-2-[3-(tert-Butyl)ureido]-3,3-dimethylbutyric Acid
Product Documents:
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Product Number | B5324 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__1H__2__2N__2O__3 = 230.31 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 101968-85-8 |
Reaxys Registry Number | 14336343 |
PubChem Substance ID | 354334535 |
MDL Number | MFCD12796012 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | 182 °C(dec.) |
Specific Rotation | -6° (C=1,AcOH) |
GHS
Related Laws:
Transport Information:
H.S.code* | 2924.19-000 |
Application
A Synthetic Intermediate of Peptidic Protease Inhibitor
This product is used as a synthetic intermediate of peptidic protease inhibitor for the potential treatment of hepatic virus infection, such as boceprevir.
References
- Discovery of (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor: A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection
- Synthesis and Process Optimization of Boceprevir: A Protease Inhibitor Drug
PubMed Literature
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