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CAS RN: 284462-37-9 | Product Number: A2617
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide

Purity: >98.0%(T)(HPLC)
Synonyms:
- 4-(4-Aminophenoxy)-N-methylpicolinamide
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
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1G |
NT$756
|
1 | 17 | It can be shipped in about 2 weeks after ordering | |
5G |
NT$1,806
|
14 | 2 | Contact Us |
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Product Number | A2617 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__3H__1__3N__3O__2 = 243.27 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 284462-37-9 |
Reaxys Registry Number | 11461032 |
PubChem Substance ID | 253659779 |
MDL Number | MFCD08692047 |
Specifications
Appearance | White to Light yellow to Light orange powder to crystalline |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 116.0 to 120.0 °C |
Properties (reference)
Melting Point | 118 °C |
GHS
Pictogram |
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Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
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Transport Information:
H.S.code* | 2933.39-000 |
Application
A Synthetic Intermediate of Sorafenib and Its Structural Analogs
This product has been used as a synthetic intermediate of protein kinase inhibitors, such as an antitumor sorafenib (BAY 43-9006) [O0599] and its structural analogs.
References
- A Scaleable Synthesis of BAY 43-9006: A Potent Raf Kinase Inhibitor for the Treatment of Cancer
- Convenient synthesis of Sorafenib and its derivatives
- Design, synthesis and biological activities of thiourea containing sorafenib analogs as antitumor agents
- Design, synthesis, activity and docking study of sorafenib analogs bearing sulfonylurea unit
PubMed Literature
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