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CAS RN: 95233-18-4 | Product Number: A2545
Atovaquone
Purity: >98.0%(T)(HPLC)
Synonyms:
- trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione
- Atavaquone
Product Documents:
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Product Number | A2545 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__2H__1__9ClO__3 = 366.84 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (<0°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 95233-18-4 |
Reaxys Registry Number | 8076827 |
PubChem Substance ID | 160871512 |
Merck Index (14) | 866 |
MDL Number | MFCD00889188 |
Specifications
Appearance | Light yellow to Brown powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Melting point | 220.0 to 224.0 °C |
Properties (reference)
Melting Point | 223 °C |
Maximum Absorption Wavelength | 494(aq. Buffer) nm |
Solubility in water | Insoluble |
Solubility (slightly sol. in) | Acetone |
Solubility (insoluble in) | Methanol |
GHS
Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
RTECS# | QJ5616500 |
Transport Information:
H.S.code* | 2914.79-000 |
Application
Atovaquone: An Antifungal Reagent against Pneumocystis jiroveci
(The product is for research purpose only.)
References
- Atovaquone - a novel broad-spectrum anti-infective drug (a review)
- New Insights Into Transmission, Diagnosis, and Drug Treatment of Pneumocystis carinii Pneumonia (a review)
- Chemotherapy against babesiosis (a review)
Application
Studies on Antimicrobial and Antimalarial Activities of Atovaquone
References
- Atovaquone, a broad spectrum antiparasitic drug, collapses mitochondrial membrane potential in a malarial parasite
- Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites
- Interactions of atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro
- A mechanism for the synergistic antimalarial action of atovaquone and proguanil
- I. K. Srivastava, A. B. Vaidya, Antimicrob. Agents Chemother. 1999, 43, 1334.
- Antiparasitic agent atovaquone
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Articles/Brochures
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