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CAS RN: 148893-10-1 | Product Number: A1797
HATU
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Purity: >98.0%(HPLC)
Synonyms:
- 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-Oxide Hexafluorophosphate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
NT$3,840
|
16 | ≥100 | It can be shipped in about 2 weeks after ordering | |
| 25G |
NT$13,280
|
1 | ≥100 | It can be shipped in about 2-3 business days after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
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in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | A1797 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__5F__6N__6OP = 380.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Moisture Sensitive,Heat Sensitive |
| CAS RN | 148893-10-1 |
| Reaxys Registry Number | 11805773 |
| PubChem Substance ID | 125307047 |
| MDL Number | MFCD00274639 |
Specifications
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
Properties (reference)
| Melting Point | 186 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
A Condensing Reagent
Experimental procedure1): L-leucine tert-butyl ester hydrochloride (1, 67 mg, 0.3 mmol), N-Fmoc-L-proline (2, 101 mg, 0.3 mmol) and HATU (171 mg, 0.45 mmol) are added to a flask under argon. Anhydrous dichloromethane (1 mL), anhydrous DMF (0.5 mL), and collidine (79 µL, 0.6 mmol) are added and stirred at room temperature for 3 hr. HCl (1 mol/L, 1 mL) is added and the reaction mixture is diluted with dichloromethane (3 mL) and washed with H2O (3 x 1.5 mL). The crude mixture is concentrated in vacuo and then purified by flash chromatography (hexane:EtOAc = 1:0 ~ 1:1) to yield 3 as a white solid (151 mg, 0.3 mmol) in 99% yield.
References
- 1)Progress toward the Total Synthesis of Lucentamycin A: Total Synthesis and Biological Evaluation of 8-epi-Lucentamycin A
- 2)The Uronium/Guanidinium Peptide Coupling Reagents: Finally the True Uronium Salts
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Other Documents
Related Products
Reagents for Condensation Reactions (HATU) (HPMC encapsulated)
| Product # | R0295 |
| CAS RN | 148893-10-1 |
| Purity / Analysis Method: |