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CAS RN: 59880-97-6 | Product Number: F1158
N-Formyl-L-methionyl-L-leucyl-L-phenylalanine
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Purity: >98.0%(HPLC)
Synonyms:
- N-Formyl-Met-Leu-Phe
- fMLF
- fMLP
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€53.00
|
1 | 21 |
|
| 100MG |
€207.00
|
Contact Us | 13 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | F1158 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__3__1N__3O__5S = 437.56 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 59880-97-6 |
| Reaxys Registry Number | 2315783 |
| PubChem Substance ID | 468591830 |
| MDL Number | MFCD00036780 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -8.0 ～ -10.0 deg(C=1, acetic acid) |
Properties (reference)
| Melting Point | 213 °C(dec.) |
| Specific Rotation | -8° (C=1,AcOH) |
GHS
Related Laws:
Transport Information:
| HS Number | 2930909599 |
Application
fMLP: A Highly Potent Leukocyte Chemoattractant
N-Formyl-Met-Leu-Phe (abbrev.: fMLP or FMLP), a bacterial peptide, is a highly potent leukocyte chemoattractant. It is a powerful "activators" of polymorphonuclear and mononuclear phagocytes. Its specific receptors have been identified on neutrophil plasma membrane which plays an important role in host defense against bacterial infections.
References
- Cellular responses to FMLP challenging: a mini-review
- Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils (a review)
- Studies on human neutrophil biological functions by means of formyl-peptide receptor agonists and antagonists (a review)
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