用于将功能性部位引入聚合物和单体的p-硝基苯碳酸酯

甲基丙烯酸2-[[(4-硝基苯氧基)羰基]氧基]乙酯(1)是一种甲基丙烯酸酯单体，可以与伯胺反应，通过聚氨酯键结合引入功能性部位。除了用于合成功能性单体¹⁾，1也可以用于将功能性部位引入到1的衍生聚合物和共聚物中^2-5)，此过程也适用于引入不符合聚合条件的功能性基团。此外，1也适用于通过原子转移自由基聚合(ATRP)或可逆加成-断裂链转移聚合(RAFT)进行聚合物合成，因此可以通过将化合物如抗肿瘤药物阿霉素³⁾、与铁离子配位的多巴胺^3,4)、与⁸⁹Zr配位的DFO⁵⁾等导入到由1组成的嵌段共聚物中，开发治疗用纳米粒子。

关键词

N1293

甲基丙烯酸2-[[(4-硝基苯氧基)羰基]氧基]乙酯

S0814

丙烯酸-N-琥珀酰亚胺酯

S0812

甲基丙烯酸 N-琥珀酰亚胺酯

文献

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