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通过全氟化碘(III)试剂脱羧反应进行可见光光氧化还原三氟甲基化反应
[双(三氟乙酰氧基)碘代]五氟苯 (1)的新应用有助于在结合光氧化还原金属催化剂下作为(异)芳烃的三氟甲基化试剂被使用。例如,卿等曾报道,1与(杂)芳烃在光氧化还原金属催化剂的存在下,用蓝光LED照射,得到相应的三氟甲基化芳基产物,产率很好。该反应可以在温和的条件下进行,副产物和碘代五氟苯可以很容易地分离。这种新方法通过使用1作为一个温和且易得到的CF3源,可进一步增加它的合成效用。
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- 1)Visible-Light Photoredox Decarboxylation of Perfluoroarene Iodine(III) Trifluoroacetates for C–H Trifluoromethylation of (Hetero)arenes