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CAS RN: 83480-29-9 | 产品编码: V0119
Voglibose
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| 规格 | 单价 | 同一天 | 2-3个工作日 | 左侧以上货期 | 数量 |
货期信息
|
|---|---|---|---|---|---|---|
| 100MG |
S$253.50
|
≥40 | 0 | 下单后约2周内可以发货 |
|
| 产品编码 | V0119 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__0H__2__1NO__7 = 267.28 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (<0°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 83480-29-9 |
| Reaxys-RN | 5430708 |
| PubChem物质ID | 160871113 |
| Merck Index (14) | 10029 |
| MDL编号 | MFCD00865496 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 163.0 to 168.0 °C |
| Specific rotation [a]20/D | +45.0 to +48.0 deg(C=1、0.1mol/LHCl |
物性（参考值）
| 熔点 | 165 °C |
| 比旋光度 [α]D | 46° (C=1,0.1mL/L HCl) |
GHS
相关法规
| RTECS# | NM7524600 |
运输信息
| HS编码* | 2922.19-000 |
应用
Voglibose: A Pseudo-Monosaccharide α-Glucosidase Inhibitor
Voglibose (AO-128) is a pseudo-monosaccharide α-glucosidase inhibitor, such as miglitol [M2302]. α-Glucosidase (also called maltase) is an enzyme, and catalyzes the hydrolysis of terminal 1,4-linked α-glucose residues of oligosaccharides and disaccharides to a single α-glucose molecule. Miglitol lowers blood sugar by inhibiting the enzyme α-glucosidase in the gastrointestinal tract, resulting in delayed glucose absorption. In addition, α-glucosidase inhibitors do not stimulate insulin release and therefore do not result in hypoglycemia. (The product is for research purpose only.)
References
- Synthesis and α-D-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potential oral antidiabetic agents
- Voglibose (Basen, AO-128), one of the most important α-glucosidase inhibitors (a review)
- Voglibose: an alpha glucosidase inhibitor (a review)
- Quantitative determination of voglibose in pharmaceutical tablets using high-performance liquid chromatography-fluorescence detection with post-column derivatization and mass spectrometric detection
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