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CAS RN: 61318-91-0 | 产品编码: U0112
Sulconazole Nitrate
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| 产品编码 | U0112 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__1__8H__1__5Cl__3N__2S·HNO__3 = 460.75 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 61318-91-0 |
| 相关CAS RN | 61318-90-9 |
| Reaxys-RN | 7965210 |
| PubChem物质ID | 468593080 |
| Merck Index (14) | 8893 |
| MDL编号 | MFCD00058163 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
物性（参考值）
| 熔点 | 152 °C(dec.) |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | NI4475000 |
运输信息
| HS编码* | 2933.29-000 |
应用
Sulconazole Nitrate: An Imidazole Antifungal Agent with Broad-Spectrum Activity
Sulconazole nitrate is an imidazole derivative antifungal agent. It possesses a broad spectrum of activity in vitro against dermatophytes, yeasts and some Gram-positive bacteria. It is a selective inhibitor of fungal cytochrome P450 dependent enzyme lanosterol 14-α-demethylase. It functions to convert lanosterol to ergosterol which is an essential component of fungal cell membrane. (The product is for research purpose only.)
References
- Sulconazole. A review of its antimicrobial activity and therapeutic use in superficial dermatomycoses
- Inhibition of cytochromes P450 by antifungal imidazole derivatives
- Comparative study of the enantiomeric resolution of chiral antifungal drugs econazole, miconazole and sulconazole by HPLC on various cellulose chiral columns in normal phase mode
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