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CAS RN: 1508-75-4 | 产品编码: T1470
技术规格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 99.0 area% |
Purity(Nonaqueous Titration) | min. 99.0 % |
Melting point | 97.0 to 100.0 °C |
NMR | confirm to structure |
物性(参考值)
熔点 | 98 °C |
最大吸收波长 | 254 nm (HCl aq.) |
溶解性(可溶于) | 氯仿, 乙醇 |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H302 : Harmful if swallowed. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
RTECS# | CY1487860 |
运输信息
HS编码* | 2933.39-000 |
应用
Tropicamide: A Muscarinic M4 Receptor Antagonist
Tropicamide is a muscarinic M4 receptor antagonist. Tropicamide produces short acting cycloplegia and mydriasis when applied as eye drops. Tropicamide has an action similar to atropine [A0754], but its cycloplegic and mydriatic effects have a more rapid onset and a shorter duration of effect. Tropicamide is slightly soluble in water and in diethyl ether, freely soluble in ethanol and in chloroform. (The product is for research purpose only.)
References
- The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors
- The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide
- Preparation and evaluation of liposomal formulations of tropicamide for ocular delivery
- Tropicamide (a review on the physical properties, synthesis, stability, metabolism and analysis)
- High-performance liquid chromatographic determination of phenylephrine and tropicamide in human aqueous humor
参考文献
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