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CAS RN: 242478-38-2 | 产品编码: S0944
Solifenacin Succinate
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| 产品编码 | S0944 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__2__3H__2__6N__2O__2·C__4H__6O__4 = 480.56 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
100MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 242478-38-2 |
| 相关CAS RN
|
242478-37-1 |
| PubChem物质ID | 253662487 |
| Merck Index (14) | 8712 |
| MDL编号 | MFCD09952287 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(total of Ion-Pair) |
| Melting point | 145.0 to 149.0 °C |
物性（参考值）
| 熔点 | 147 °C |
| 溶解性（微溶于） | 乙醇 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | NW7136000 |
运输信息
| HS编码* | 2933.99-000 |
应用
Solifenacin Succinate: Selective M3 Muscarinic Receptor Antagonist
Solifenacin succinate is a selective M3 muscarinic receptor antagonist. It is used for the treatment of overactive bladder (OAB). For your reference, [P2215] is a key synthetic intermediate of solifenacin succinate. (The product is for research purpose only.)
References
- M3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland
- In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats
- Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells
- Synthesis and Antimuscarinic Properties of Quinuclidin-3-yl 1,2,3,4-Tetrahydroisoquinoline-2-carboxylate Derivatives as Novel Muscarinic Receptor Antagonists
- Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents
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