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CAS RN: 135159-51-2 | 产品编码: S0914
Sarpogrelate Hydrochloride
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纯度/分析方法: >98.0%(T)(HPLC)
别名：
- 盐酸沙格雷酯
- 4-[[1-(二甲基氨基)-3-[2-[2-(3-甲氧基苯基)乙基]苯氧基]-2-丙酰基]氧基]-4-氧代丁酸盐酸盐
- 4-[[1-(二甲基氨基)-3-[2-(3-甲氧基苯乙基)苯氧基]丙烷-2-基]氧基]-4-氧代丁酸盐酸盐
- 氢化琥珀酸1-(二甲氨基)-3-[2-(3-甲氧基苯乙基)苯氧基]-2-丙酯盐酸盐
- 4-[[1-(Dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-2-propanyl]oxy]-4-oxobutanoic Acid Hydrochloride
- 4-[[1-(Dimethylamino)-3-[2-(3-methoxyphenethyl)phenoxy]propan-2-yl]oxy]-4-oxobutanoic Acid Hydrochloride
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产品文档：
| 产品编码 | S0914 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__2__4H__3__1NO__6·HCl = 465.97 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,湿气 (吸湿) |
| 包装和容器 | 250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 135159-51-2 |
| Reaxys-RN | 3643699 |
| MDL编号 | MFCD00887582 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Precipitation Titration) | min. 98.0 % |
| Melting point | 151.0 to 155.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 152 °C |
GHS
相关法规
| RTECS# | EJ9965500 |
运输信息
| HS编码* | 2922.19-000 |
应用
Sarpogrelate Hydrochloride: A Selective 5-HT2 Receptors Antagonist
The serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into seven subfamilies. Among them, 5-HT2 receptors are associated with the contraction of vascular smooth muscle and platelet aggregation. Sarpogrelate hydrochloride (MCI-9042) is a selective 5-HT2 receptors antagonist, which inhibits the 5-HT2 induced platelet aggregation, vasoconstriction and vascular smooth muscle proliferation. (The product is for research use only.)
References
- MCI-9042, a new antiplatelet agent is a selective S2-serotonergic receptor antagonist
- Functions of 5-HT2A receptor and its antagonists in the cardiovascular system (a review)
- 5-Hydroxytryptamine and Its Receptors in Systemic Vascular Walls (a review)
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