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CAS RN: 138-52-3 | 产品编码: S0003
Salicin
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -60.0 to -64.0 deg(C=3, H2O) |
物性（参考值）
| 熔点 | 200 °C |
| 比旋光度 [α]D | -62° (C=3,H2O) |
| 水溶性 | 可溶 |
| 溶解性（不溶于） | 乙醚, 氯仿 |
GHS
相关法规
| RTECS# | LZ5901700 |
运输信息
| HS编码* | 2938.90-000 |
应用
Salicin: An Alcoholic β-Glucoside Derived from Willow Bark with Anti-Inflammatory Activity
Salicin is an alcoholic β-glucoside derived from willow bark which has been traditionally used as an anti-inflammatory, antipyretic, and analgesic medicine.1,2) Salicin acts as a non-selective COX inhibitor, and effects very similar to acetylsalicylic acid [A2262].3) Recently, various studies have demonstrated that the anti-inflammatory activity of willow bark extract is associated with down regulation of the inflammatory mediators tumor necrosis factor-α and nuclear factor-kappa B.2) In addition, some studies have been reported that salicin acts as an agonist on the bitter taste receptor, TAS2R16.4) (The product is for research purpose only.)
References
- 1) Willow bark extract: the contribution of polyphenols to the overall effect (a review)
- 2) Efficacy and Safety of White Willow Bark (Salix alba) Extracts (a review)
- 3) Structural and Functional Basis of Cyclooxygenase Inhibition
- 4) The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides
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