Maximum quantity allowed is 999
请选择数量
CAS RN: 90098-04-7 | 产品编码: R0085
Rebamipide
×
![]()
×
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
物性（参考值）
| 熔点 | 290 °C(dec.) |
GHS
相关法规
| RTECS# | VC2518500 |
运输信息
| HS编码* | 2933.49-000 |
应用
Rebamipide: A Quinolinone Analog for Gastric Mucosal Protection
Rebamipide (OPC-12759), a 2(1H)-quinolinone analog, is used as an anti-gastritis and anti-gastric ulcer agent. It has been reported to have various activities in the gastric mucosa, such as stimulation of prostaglandin and mucus glycoprotein synthesis, inhibition of reactive oxygen species, inflammatory cytokines and chemokines, and inhibition of neutrophils activation. Furthermore, inhibition of gastric tumor growth by rebamipide has also been reported. In addition, rebamipide is used as a therapeutic adjunct for the treatment of infections caused by Helicobacter pylori. For your reference, we also have a related synthetic intermediate [O0468] of rebamipide. (The product is for research purpose only.)
References
- Studies on 2 (1H)-Quinolinone Derivatives as Gastric Antiulcer Active Agents. 2-(4-Chlorobenzoylamino)-3-[2 (1H)-quinolinon-4-yl] propionic Acid and Related Compounds
- Gastric mucosal protection by OPC-12759, a novel antiulcer compound, in the rat
- Hydroxyl radical scavenging by rebamipide and related compounds: electron paramagnetic resonance study
- 15th Anniversary of Rebamipide: Looking Ahead to the New Mechanisms and New Applications (a review)
- Rebamipide: a gastrointestinal protective drug with pleiotropic activities (a review)
- Optimization of forced degradation using experimental design and development of a stability-indicating liquid chromatographic assay method for rebamipide in bulk and tablet dosage form
应用
Induction of Cyclooxygenase-2 (COX-2) in Rat Gastric Mucosa by Rebamipide
Reference
- Induction of Cyclooxygenase-2 in Rat Gastric Mucosa by Rebamipide, a Mucoprotective Agent
- M. Yasumaru, H. Iijima, Y. Okuda, Y. Sasaki, M. Hori, S. Kawano, J. Pharmacol. Exp. Ther. 2000, 295, 447.
参考文献
TCIMail
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。