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CAS RN: 6724-53-4 | 产品编码: P3145
Perhexiline Maleate
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| 产品编码 | P3145 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__9H__3__5N·C__4H__4O__4 = 393.57 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,加热 |
| CAS RN | 6724-53-4 |
| Reaxys-RN | 6459396 |
| MDL编号 | MFCD00057329 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
GHS
相关法规
| RTECS# | TM7068000 |
运输信息
| HS编码* | 2933.39-000 |
应用
Perhexiline Maleate: A Carnitine Palmitoyltransferase 1 (CPT1) and 2 (CPT2) Inhibitor
Perhexiline maleate is a carnitine palmitoyltransferase 1 (CPT1) and 2 (CPT2) inhibitor originally developed in the 1970s as an anti-anginal drug. CPT1/2 are mitochondrial enzymes responsible for the mitochondrial uptake of long chain fatty acids. Perhexiline maleate reduces fatty acid metabolism by inhibiting CPT1/2.1,2) Recently, perhexiline maleate has also received attention as an anticancer agent.3) (The product is for research use only.)
References
- 1) Systematic review of the efficacy and safety of perhexiline in the treatment of ischemic heart disease
- 2) Perhexiline (a review)
- 3) Perhexiline: Old Drug, New Tricks A Summary of Its Anti-Cancer Effects
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