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CAS RN: 17673-25-5 | 产品编码: P2732
Phorbol
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| 产品编码 | P2732 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__2__0H__2__8O__6 = 364.44 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (-20°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 25MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 17673-25-5 |
| Reaxys-RN | 2341335 |
| PubChem物质ID | 468592695 |
| Merck Index (14) | 7332 |
| MDL编号 | MFCD00065450 |
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 251 °C(dec.) |
| 比旋光度 [α]D | 93° (C=1,H2O) |
| 水溶性 | 可溶 |
| 溶解性（可溶于） | 乙醇, 丙酮 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | GZ0600000 |
运输信息
| HS编码* | 2914.40-000 |
应用
Phorbol: A Tetracyclic Diterpene for the Synthesis of Various its Diesters Known for their Tumor Promoting Activity
Phorbol is a tetracyclic diterpene originally isolated from croton oil.1,2) It is used as a starting compound for the synthesis of various phorbol diesters, which generally known for their tumor promoting activity and often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC).3)
References
- 1) A rapid method for isolating phorbol from croton oil
- 2) Nineteen-step total synthesis of (+)-phorbol
- 3) Phorbol esters: Structure, biological activity, and toxicity in animals (a review)
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