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CAS RN: 54-95-5 | 产品编码: P0046
1,5-Pentamethylenetetrazole
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 59.0 to 63.0 °C |
| Solubility in Water | almost transparency |
物性（参考值）
| 熔点 | 60 °C |
| 沸点 | 194 °C/12 mmHg |
| 水溶性 | 可溶 |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | XF8225000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2933.99-000 |
应用
Reagents convulsion or paralysis model
References
- Studies on prostaglandin F2 alpha formation caused by pentametylenetetrazol-induced convulsions in rat brain
- AP-1 and CRE DNA binding activities in rat brain following pentylenetetrazole induced seizures
- A neuropharmacological analysis of PTZ-induced kindling in mice
- Upregulation of NMDA receptors in hippocampus and cortex in the pentylenetetrazol-induced "kindling" model of epilepsy
- Effects of compounds acting on GABA(B) receptors in the pentylenetetrazole kindling model of epilepsy in mice
- Changes in AMPA receptor binding and subunit messenger RNA expression in hippocampus and cortex in the pentylenetetrazole-induced 'kindling' model of epilepsy
- Interactions of tiagabine with ethosuximide in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves
- Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves
- J. J. Luszczki, M. Krzyzanowski, M. J. Swiader, Adv. Med. Sci. 2009, 54, 75
- Effect of ACEA--a selective cannabinoid CB1 receptor agonist on the protective action of different antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model
参考文献
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