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CAS RN: 189224-26-8 | 产品编码: O0660
Ozagrel Sodium
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| 产品编码 | O0660 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__3H__1__1N__2NaO__2 = 250.23 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 189224-26-8 |
| MDL编号 | MFCD00875845 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
| 溶解性（可溶于） | 甲醇 |
| 溶解性（不溶于） | 乙醇 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H371 : May cause damage to organs. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P405 : Store locked up. |
相关法规
运输信息
| HS编码* | 2933.29-000 |
应用
Ozagrel Sodium: A Selective Thromboxane A2 (TXA2) Synthetase Inhibitor
Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets during hemostasis and is also a potent constrictor of smooth muscle. Ozagrel sodium is a selective TXA2 synthetase inhibitor and blocks platelet aggregation and reduces bronchial muscle hypersensitivity. In clinical, it has been used as a therapeutic agent for ischemic heart diseases, thromboembolic disorders, cerebral circulatory disorders and asthma. (The product is for research purpose only.)
References
- Pharmacological studies on the TXA synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046)
- Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets
- Thromboxane A2 inhibition: Therapeutic potential in bronchial asthma (a review)
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